DNA Mismatch Repair in Advanced Metastatic Prostate Carcinoma: Clinical Perspective
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چکیده
Submit Manuscript | http://medcraveonline.com Abbreviations: PCa: Prostate Carcinoma; CRPC: Castrationresistant Prostate Carcinoma; MMR: Mismatch Repair; ADT: Androgen-deprivation Therapy; OS: Overall Survival; NER: Nucleotide Excision Repair; BER: Base Excision Repair; HDR: Homology Directed Repair; HR: Homologous Recombination; DDR: DNA Damage Response; NHEJ: Non-homologous End Joining; SSB: Single Strand Breaks; PARP: Poly (adenosine diphosphate [ADP]–ribose) Polymerase; PARPi: PARP Inhibitors
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